Post #17660 by kahukini on Tue, Dec 31, 2002 3:06 PM

"Millions of people take a drug like Tylenol safely, but for someone who is a regular alcohol user, it can wipe out the liver."

• Eugene Schiff, M.D., president of the American Association for the Study of Liver Diseases and director of the Center for Liver Diseases at University of Miami's School of Medicine.

It's one of the most dramatic things that can happen to your body. Literally one day you are fine and the next day you will die if you don't get to the hospital and have a liver transplant. The FDA considers a "significant" rate of severe injury to be 1 in 50,000 exposures or greater. I don't like those odds. Such drugs get significant limitations on their use including vigorous warnings on the packaging. The FDA's list of drugs with significant limitations due to liver problems includes:

Niaspan Extended Release Tablets (niacin)
Dantrium (dantrolene)
Tylenol (acetaminophen)
Normodyne (labetalol)
Cylert (pemoline)
Felbatol (felbamate)
Zyflo (zileuton)
Tasmar (tolcapone)
Trovan (trovafloxacin, alatrofloxacin)