Post #536654 by Pittsburgh pauly on Wed, Jun 16, 2010 8:22 AM

Too bad the Coral Court isn't still around in St Louis.
http://www.coralcourt.com/main.html
Check out the Ted Drewes ice cream stand, it's an institution in StL.
http://www.teddrewes.com/Drewes.asp
If you swing a little north in the WV panhandle you can hit the Fiestaware factory in Chester.
http://www.fiestafactorydirect.com/
and the World's Largest Teapot!
Then coming towards Pittsburgh you could check out Meadowcroft Rockshelter, the oldest site of human habitation in North America!
http://www.heinzhistorycenter.org/meadowcroft.aspx
or go more southern to Canonsburg, the City of Antiques (there's a great mid-century store) and see the Perry Como statue.

Pittsburgh has tiki! The Tiki Lounge! http://www.tikilounge.biz but I'd say go during the week, weekends are top40 dance, hip hop (I know, I know!)

Then ride the inclines (funicular) to one of the best views in the US on Mount Washington, also, St Anthony's has the largest collection of religious relics outside of the Vatican, and Trundle Manor is a new steampunk roadside attraction/cabinet of curiosities. Heading east there's Monroeville Mall where Dawn of the Dead was filmed (not much to see, but I hear there's a "museum" to it in one of the toy stores), in Indiana PA there's a Jimmy Stewart statue and museum, in Johnstown there's the World's Steepest Vehicular Inclined Plane http://www.inclinedplane.com/ in Altoona there's the oldest roller coaster in America http://www.lakemontparkfun.com/, and Horseshoe curve.
If you stay on a more southern route there's Frank Lloyd Wright's Fallingwater (a most for everyone at some point) as well as his Kentuck Knob and Polymath Park (one of a handful of Wright buildings you can spend the night in...for a price) also some Muffler men and shaped buildings, all on Roadside America.
hope that gives ya some ideas for this neck of the woods.